Hydration / Barrier

Panthenol (Provitamin B5)

INCI: Panthenol · CAS 81-13-0

Panthenol is the provitamin form of vitamin B5, a versatile humectant used in skincare and haircare for hydration, soothing and improved softness.

INCIPanthenol
CAS81-13-0
Also known asProvitamin B5, D-Panthenol
Use leveltypically 1–5%
Solubilitywater-soluble
pH / stabilitystable ~4–7
RegulatoryListed in EU CosIng

What it does

  • Hydrates and helps improve skin softness and suppleness.
  • Soothes and supports the barrier, useful after irritation.
  • In hair, improves moisture, manageability and shine.

How it works

Panthenol is converted in the skin to pantothenic acid (vitamin B5), a component of coenzyme A involved in skin metabolism and repair. As a humectant it also draws and holds water, and it is widely documented to have soothing, barrier-supporting properties, which is why it appears in after-sun, post-procedure and sensitive-skin products.

Use level

Typical use level
typically 1–5%

Commonly 1–5% in both skincare and haircare; around 1–2% is typical for general use.

Formulation considerations

  • Water-soluble; add to the water phase.
  • Most stable around pH 4–7; strongly acidic or alkaline conditions over time can hydrolyse it.
  • Compatible with most actives; a reliable soothing/humectant workhorse.

What it pairs with & what to avoid

Pairs well with

  • Niacinamide, allantoin, centella (soothing)
  • Hyaluronic acid, glycerin (hydration)
  • Common in leave-on and rinse-off hair products

Use with care / avoid

  • Prolonged extreme pH (hydrolysis)

Regulatory status

Panthenol is listed in the EU CosIng database and is a long-established, well-tolerated cosmetic ingredient.

Common questions

What does panthenol do for skin?

It hydrates, soothes and supports the barrier, and is popular in sensitive-skin, after-sun and post-procedure products.

What percentage of panthenol should I use?

Typically 1–5%, with 1–2% common for everyday products.

Is panthenol good for hair?

Yes; it improves moisture, softness, manageability and shine in both leave-on and rinse-off products.

Related monographs

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