What it does
- Gently exfoliates the skin surface with minimal irritation.
- Hydrates (it is also a humectant) and provides antioxidant support.
- A good option for sensitive skin and for building acid tolerance.
How it works
Gluconolactone is a polyhydroxy acid — a larger, multi-hydroxyl molecule that exfoliates like an AHA but more slowly and gently, with humectant and antioxidant properties. It is widely documented as suitable for sensitive and rosacea-prone skin and is generally considered less photosensitising than classic AHAs.
Use level
- Typical use level
- typically 3–10%
Commonly used at 3–10% at low pH. A gentle entry point to chemical exfoliation.
Formulation considerations
- Water-soluble; low pH drives exfoliation.
- Also acts as a humectant, so it is less drying than some acids.
- Generally well tolerated by sensitive skin.
What it pairs with & what to avoid
Pairs well with
- Hydrators and soothing actives
- Niacinamide
Use with care / avoid
- Over-layering with other strong acids
Regulatory status
Gluconolactone is listed in the EU CosIng database and is a well-established gentle exfoliant.
Common questions
What is a PHA?
A polyhydroxy acid — a gentle, larger-molecule exfoliant (such as gluconolactone) that also hydrates, suiting sensitive skin.
Is gluconolactone good for sensitive skin?
Yes; PHAs are widely documented as gentle and are often recommended for sensitive and rosacea-prone skin.
What percentage of gluconolactone is used?
Commonly 3–10% at low pH.