Soothing / Sensitive

Allantoin

INCI: Allantoin · CAS 97-59-6

Allantoin is a gentle, widely used soothing and skin-conditioning active that helps calm the skin, support smoothness and improve comfort.

INCIAllantoin
CAS97-59-6
Use leveltypically 0.1–2%
Solubilitylimited water solubility (~0.5%)
pH / stabilitystable ~4–8
RegulatoryListed in EU CosIng

What it does

  • Soothes and helps calm sensitive or irritated skin.
  • Conditions and smooths, supporting a soft, comfortable feel.
  • Supports the skin's natural recovery.

How it works

Allantoin is widely documented as a soothing, keratolytic and skin-conditioning agent that promotes a smoother, more comfortable surface and supports the skin's natural repair. It is extremely gentle, which is why it appears across sensitive-skin, baby and after-sun products.

Use level

Typical use level
typically 0.1–2%

Commonly used at 0.1–2%. Its water solubility is limited (around 0.5%), so higher levels need careful formulation to avoid recrystallisation.

Formulation considerations

  • Limited water solubility (about 0.5%); above this it can recrystallise.
  • Add to the water phase with adequate heat/dissolution.
  • Stable around pH 4–8 and broadly compatible.

What it pairs with & what to avoid

Pairs well with

  • Panthenol, centella, colloidal oatmeal (soothing)
  • Most hydrating and barrier actives

Use with care / avoid

  • Overloading beyond its solubility limit (crystallisation)

Regulatory status

Allantoin is listed in the EU CosIng database and is a long-established, gentle cosmetic ingredient.

Common questions

What does allantoin do for skin?

It soothes, conditions and smooths, supporting comfort and recovery; it is very gentle.

What percentage of allantoin is used?

Typically 0.1–2%, keeping in mind its limited water solubility (around 0.5%).

Is allantoin safe for sensitive skin?

Yes; it is widely used in sensitive-skin, baby and after-sun products.

Related monographs

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