Hydration / Barrier

Pentylene Glycol

INCI: Pentylene Glycol · CAS 5343-92-0

Pentylene glycol is a multifunctional glycol used in skincare as a humectant and solvent that also provides mild antimicrobial activity, helping support a formula's preservation.

INCIPentylene Glycol
CAS5343-92-0
Also known asmultifunctional glycol
Use leveltypically 1–5%
Solubilitywater-miscible
pH / stabilitybroad
RegulatoryListed in EU CosIng

What it does

  • Hydrates and improves texture.
  • Acts as a solvent for actives and preservatives.
  • Provides mild antimicrobial support (a preservative-booster).

How it works

Pentylene glycol is widely documented as a humectant/solvent with mild antimicrobial activity, so it is popular in low-preservative and 'preservative-free-claim' systems as part of a hurdle approach. It is gentle and multifunctional.

Use level

Typical use level
typically 1–5%

Commonly used at 1–5%; often part of a preservative-boosting system rather than a stand-alone preservative.

Formulation considerations

  • Water-miscible; add to the water phase.
  • Supports (but does not replace) a robust preservation system.
  • Gentle and broadly compatible.

What it pairs with & what to avoid

Pairs well with

  • Other glycols and humectants
  • Preservative systems

Use with care / avoid

  • Not a stand-alone preservative — pair with a proven system

Regulatory status

Pentylene glycol is listed in the EU CosIng database and is a well-established multifunctional ingredient.

Common questions

What does pentylene glycol do?

It hydrates, solubilises actives and provides mild antimicrobial support as a preservative-booster.

Is pentylene glycol a preservative?

It offers mild antimicrobial support but should be paired with a proven preservation system, not used alone.

What percentage of pentylene glycol is used?

Commonly 1–5%.

Related monographs

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