Brightening / Pigmentation

N-Acetyl Glucosamine (NAG)

INCI: Acetyl Glucosamine · CAS 7512-17-6

N-acetyl glucosamine (NAG) is an amino sugar used in skincare to support a more even tone and hydration, often paired with niacinamide as a hyaluronic-acid precursor.

INCIAcetyl Glucosamine
CAS7512-17-6
Also known asNAG, amino sugar
Use leveltypically 1–4%
Solubilitywater-soluble
pH / stabilitybroad
RegulatoryListed in EU CosIng

What it does

  • Supports a more even, brighter-looking tone.
  • Supports hydration (a building block of hyaluronic acid).
  • Works synergistically with niacinamide.

How it works

NAG is an amino sugar and a precursor in the skin's own hyaluronic-acid synthesis. It is widely documented to help with the look of uneven tone and to support hydration, and is frequently combined with niacinamide, which is documented to enhance its tone benefits.

Use level

Typical use level
typically 1–4%

Commonly used at 1–4%. Often formulated with niacinamide.

Formulation considerations

  • Water-soluble; add to the water phase.
  • Broadly compatible and gentle.
  • Pairs particularly well with niacinamide.

What it pairs with & what to avoid

Pairs well with

  • Niacinamide (classic pairing)
  • Hyaluronic acid, humectants

Use with care / avoid

  • No notable incompatibilities

Regulatory status

Acetyl glucosamine is listed in the EU CosIng database and is a well-established cosmetic ingredient.

Common questions

What does N-acetyl glucosamine do?

It supports a more even tone and hydration, and works synergistically with niacinamide.

What percentage of NAG is used?

Commonly 1–4%.

Can I use NAG with niacinamide?

Yes; the two are a well-known pairing for tone and hydration.

Related monographs

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