What it does
- Support skin repair and renewal processes.
- Support firmness and a smoother, healthier-looking complexion.
- A well-known signal-peptide active.
How it works
Copper tripeptide-1 (GHK-Cu) is a copper-bound tripeptide widely documented to support wound-healing-related and collagen-related pathways in skin. It carries a characteristic blue tint. Because it is a metal complex, it is usually kept away from strong direct acids and certain antioxidants within the same formula.
Use level
- Typical use level
- low levels (about 0.05–2%, product-dependent)
Used at low, product-dependent levels (often around 0.05–2%). Follow the supplier's guidance for the specific raw material.
Formulation considerations
- Water-soluble; naturally blue-tinted.
- Formulate in mildly acidic to neutral systems.
- Generally kept separate from strong direct acids and high-dose vitamin C in the same phase.
What it pairs with & what to avoid
Pairs well with
- Hydrators and barrier actives
- Niacinamide (commonly combined)
Use with care / avoid
- Direct combination with strong acids or high-dose vitamin C in the same formula
Regulatory status
Copper tripeptide-1 is listed in the EU CosIng database and is a well-established peptide active.
Common questions
What do copper peptides do?
They are signal peptides widely documented to support skin repair, firmness and a healthier-looking complexion.
Can I use copper peptides with vitamin C?
Many formulators keep them apart within the same product, as strong acids/antioxidants can interfere; they can often be used at different times in a routine.
Why are copper peptides blue?
The copper complex gives them a characteristic blue tint.