Hydration / Barrier

Ectoin

INCI: Ectoin · CAS 96702-03-3

Ectoin is a biotech-derived extremolyte (a compatible-solute osmolyte) used in skincare as a molecular shield that supports hydration, barrier resilience and defence against environmental stress.

INCIEctoin
CAS96702-03-3
Also known asExtremolyte
Use leveltypically 0.3–2%
Solubilityfreely soluble in water
pH / stabilitystable pH 3.0–12.0
RegulatoryListed in EU CosIng

What it does

  • Binds water into a structured shell for lasting hydration.
  • Helps protect skin cells and proteins against UV, pollution and thermal stress.
  • Supports barrier function and helps calm stressed skin.

How it works

Ectoin is produced by microorganisms living in extreme environments as a compatible solute. It is widely documented to form an ordered hydration shell (the 'ectoin hydro-complex') around cell membranes and biomolecules, stabilising them under osmotic, UV, pollution and heat stress without interfering with cell function. This is the basis of its hydration, barrier and anti-pollution positioning.

Use level

Typical use level
typically 0.3–2%

Commonly used at 0.3–2%. It is effective at low levels and very gentle.

Formulation considerations

  • Freely water-soluble; add to the water phase.
  • Exceptionally stable across a very broad pH range and robust to heat.
  • Broadly compatible with other actives.

What it pairs with & what to avoid

Pairs well with

  • Hyaluronic acid, glycerin, betaine, trehalose (hydration/osmolyte stack)
  • Barrier lipids
  • Antioxidants (environmental defence)

Use with care / avoid

  • No notable incompatibilities

Regulatory status

Ectoin is listed in the EU CosIng database and is a well-established cosmetic active.

Common questions

What is ectoin used for?

Hydration, barrier support and defence against environmental stress such as UV and pollution, via its water-structuring osmolyte action.

What percentage of ectoin should I use?

Typically 0.3–2%; it is effective at low levels.

Is ectoin good for sensitive skin?

Yes; it is very gentle and is widely used in soothing and anti-pollution products.

Related monographs

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