What it does
- Replenish the skin's own barrier lipids to restore resilience.
- Reduce water loss and improve long-term hydration.
- Help calm dry, compromised and sensitive skin.
How it works
The skin barrier is built from a lipid matrix of ceramides, cholesterol and fatty acids. Ceramides are the largest lipid class in this matrix, and Ceramide NP (ceramide 3) is one of the most abundant. Replenishing ceramides is widely documented to help rebuild the lamellar structure of the barrier and reduce transepidermal water loss. Barrier repair is generally best when ceramides are combined with cholesterol and fatty acids in a physiological ratio.
Use level
- Typical use level
- typically 0.1–1% (often lower)
Individual ceramides are effective at low levels, commonly around 0.1–1% (often lower). They are most effective as part of a balanced lipid blend rather than alone.
Formulation considerations
- Oil-soluble and often waxy; require heat and proper emulsification to incorporate evenly.
- Best combined with cholesterol and fatty acids in a physiological ratio.
- Stable once properly emulsified.
What it pairs with & what to avoid
Pairs well with
- Cholesterol and fatty acids (physiological barrier blend)
- Squalane and other emollients
- Niacinamide (supports the skin's own ceramide production)
- Humectants such as glycerin and hyaluronic acid
Use with care / avoid
- Using in poorly emulsified systems (uneven delivery)
Regulatory status
Ceramides, including Ceramide NP, are listed in the EU CosIng database and are well-established barrier-repair ingredients.
Common questions
What do ceramides do for skin?
They replenish the skin's own barrier lipids, helping restore a resilient, well-hydrated barrier and reduce water loss.
What is Ceramide NP?
Ceramide NP (ceramide 3) is one of the most abundant ceramides in healthy skin and a common choice in barrier-repair products.
What percentage of ceramides should I use?
Individual ceramides work at low levels, commonly around 0.1–1%, and are most effective within a balanced lipid blend.
Do ceramides work better with other ingredients?
Yes; barrier repair is generally best when ceramides are combined with cholesterol and fatty acids in a physiological ratio.