Biotechnology-derived Halomonas elongata ferment extract produced via halophile fermentation — a proprietary process that induces stress-responsive Ectoin secretion without cell lysis. Delivers 1% Ectoin as a post-biotic ferment with synergistic bioactive compounds from the fermentation broth. Heat-stable, pH-stable, and uniquely positioned in the post-biotic skincare space.
Aqua, Glycerin, Butylene Glycol, Halomonas Ferment Extract, Ectoin, Citric Acid
Aqua: 7732-18-5 · Glycerin: 56-81-5 · Butylene Glycol: 107-88-0 · Halomonas Ferment Extract: 2244463-39-0 · Ectoin: 96702-03-3 · Citric Acid: 77-92-9
Ectoin (CAS: 96702-03-3) is the primary active at 1% w/w. Full ferment profile, post-biotic characterization, and batch CoA in TDS.
Independent in-vitro and in-vivo testing under a validated PM2.5 pollution-stress model, plus real batch release data. Full study reports available on request.
Pre-treatment with 3% Halo-Shield™ restored PM2.5-stressed keratinocyte viability from 68% toward the unstressed baseline (93%) and suppressed inflammatory cytokine release — p<0.001 vs placebo on every endpoint. Concurrent Nrf2/HO-1 up-regulation is the mechanistic signature of ectoin's osmolyte-driven antioxidant response.
22 healthy adults, paired baseline vs Day 28 (p<0.001). Rising hydration alongside falling water loss is the classic signature of a strengthening skin barrier — well tolerated, no adverse reactions reported.
Stable across pH 4 – 9 — broadly compatible with cosmetic actives, emulsifiers and surfactants; not oxygen- or light-sensitive. Orange marker: the pH measured on the latest released batch.
Self-preserving via high glycol content. No added preservatives, anti-oxidants, or chelating agents. Fragrance-free — 0 of 26 EU-declarable allergens present.
Sources: Halo-Shield™ Technical Dossier SBCT-HSB-001 — Report SBCT-HSB-IV-001 (in-vitro anti-pollution), Report SBCT-HSB-IVV-001 (in-vivo hydration & barrier), and Certificate of Analysis, Batch HSBFE-2510-001.
Ectoin forms a structured hydration shell (Ectoin Hydro-Complex) around proteins and cell membranes. Protects against UV radiation, heavy metals, pollution particulates, and thermal stress. Literature-supported barrier improvement after 7 days.
Unlike purified Ectoin, Halo-Shield delivers the full Halomonas ferment filtrate — including amino acids, compatible solutes, and metabolic byproducts. Post-biotic activity supports the skin microbiome and provides additional anti-inflammatory benefits.
Ectoin activates the Nrf2 transcription factor — the master regulator of the cell's antioxidant defense system. Upregulates endogenous protective enzymes (HO-1, NQO1) for sustained cellular defense.
Ectoin's membrane-stabilizing effect protects keratinocytes against PM2.5 and PM10 particulate-induced inflammation. Clinically relevant for urban skincare formulations targeting pollution-exposed skin.
Produced via halophile fermentation — cells release Ectoin without lysis. The intact ferment is heat-stable and compatible with standard cosmetic manufacturing temperatures.
Betaine provides synergistic osmotic regulation and anti-irritancy activity — complementing Ectoin's cellular protection mechanism at the membrane level.
Halomonas elongata is cultivated in controlled bioreactor conditions optimized for growth and Ectoin biosynthesis. The halophilic bacteria naturally produces Ectoin as an osmotic stress response compound.
Cells are subjected to hypotonic stress by diluting the growth medium. Osmotic pressure change causes cells to actively secrete Ectoin into the surrounding medium — without cell death or lysis.
Ectoin-rich supernatant is harvested while living cells are recovered and returned to hypertonic medium to re-accumulate Ectoin. Cells can be "milked" multiple times — sustainable, low-waste process.
The harvested ferment filtrate contains Ectoin plus co-secreted post-biotic compounds. Formulated into the SBCT humectant chassis — ready for direct incorporation into finished formulations.
| Parameter | Specification |
|---|---|
| Usage Level | 1.0 – 5.0% (recommended: 2.0 – 3.0%) |
| Ectoin Delivered | At 2% usage: 200 µg/g Ectoin in finished formulation. At 5% usage: 500 µg/g Ectoin. |
| Incorporation | Add to aqueous phase at ≤40°C. Heat-stable — compatible with standard processing temperatures. Stir gently. |
| Compatibility | Broad compatibility. Avoid strong oxidizing agents. Suitable for use with retinol, AHAs, niacinamide, vitamin C derivatives, and peptides. |
| Storage | Store at 15–25°C, protected from sunlight. Shelf life 24 months. |
Request the full TDS with Ectoin quantification data, or order a 1 kg evaluation sample.